Copper Tripeptide-1(GHK-Cu) is a natural copper complex, which was initially found in human plasma, but recently in saliva and urine. Copper peptide is a small natural protein fragment, which has high affinity for copper ion and is very important for human normal function. Copper Tripeptide-1(GHK-Cu) has many functions in human body, including promoting wound healing, attracting immune cells, antioxidant and anti-inflammatory effects, stimulating collagen and glycosaminoglycan synthesis of skin fibroblasts, and promoting vascular growth.
There is evidence that it is a feedback signal after tissue injury. It seems to be a powerful protective tissue. It is an anti-inflammatory agent, which can control the oxidative damage after tissue damage. In addition, it plays an important role in signal transduction of tissue remodeling, removing damaged / scarred tissue and generating new healthy tissue.
These positive effects decrease with age, because the concentration of Copper Tripeptide-1(GHK-Cu) in human body decreases with age. As a result, inflammation, cancer activity and tissue destruction increased. In plasma, Copper Tripeptide-1(GHK-Cu) level was about 200ng / ml at the age of 20. By the age of 60, the level dropped to 80 ng / ml.
Benefits of Copper Tripeptide-1(GHK-Cu):
Tighten loose skin and reverse thinning of aging skin
Repairing protective skin barrier protein
Improve skin's firmness, elasticity and clarity
Reduce the depth of fine lines and wrinkles, and improve the skin structure of the elderly
Smooth rough skin
Reduce light damage, mottled pigmentation, skin spots and damage
Improve overall skin appearance
Stimulate wound healing
Protect skin cells from UV radiation
Reduce inflammation and free radical damage
Increase hair growth and thickness, increase hair follicle size
Copper Tripeptide-1(GHK-Cu) Research:
As Copper Tripeptide-1(GHK-Cu) plays an important role in skin biology, it is widely used in cosmetics as a repair and anti-aging component.
GHK stimulates the synthesis and decomposition of collagen and glycosaminoglycan, and regulates the activity of metalloproteinases and their inhibitors. It stimulates collagen, dermatan sulfate, chondroitin sulfate, and small protein polysaccharides, decorin. It can also restore the viability of fibroblasts after radiotherapy. This molecule attracts immune cells and endothelial cells to the site of injury. Accelerate wound healing of skin, hair follicles, gastrointestinal tract and bone tissue. In cosmetics, it is found that it can tighten the loose skin, improve the elasticity, density and hardness of the skin, reduce fine lines and wrinkles, reduce light damage and pigmentation, and increase the proliferation of keratinocytes.
Copper Tripeptide-1(GHK-Cu) FACIAL STUDIES:
Copper peptide Copper Tripeptide-1(GHK-Cu) is widely used in anti-aging cosmetics (INCI Name: copper Tripeptide-1). Some control facial studies confirmed the anti-aging, firming and anti wrinkle activities of copper peptide Copper Tripeptide-1(GHK-Cu). Abdulghani et al. It is confirmed that the cream containing Copper Tripeptide-1(GHK-Cu) can increase the collagen content in the photoaging skin of 20 female volunteers, which is superior to vitamin C and retinoic acid. Leyden et al. The results showed that compared with placebo, the skin relaxation, clarity and appearance were significantly improved, the depth of fine lines and wrinkles was reduced, and the skin density and thickness were increased. Copper Tripeptide-1(GHK-Cu) eye cream is better than vitamin K eye cream. Finkley et al. A facial study of 12 women was conducted in 67 women. It was reported that according to the histological analysis of the biopsies, Copper Tripeptide-1(GHK-Cu) cream two times a day can improve the appearance of aging skin, increase the thickness, reduce wrinkles, and stimulate the proliferation of dermal keratinocytes. In the same study, Copper Tripeptide-1(GHK-Cu) was found to be non-toxic and non irritant.
HAIR GROWTH BENEFITS OF Copper Tripeptide-1(GHK-Cu):
Copper Tripeptide-1(GHK-Cu) and its analogues have a strong stimulating effect on hair growth. The simulation efficiency of GHK copper synthesis is similar to that of 5% minoxidil.
Copper peptide is a small protein fragment with high affinity for copper ion. In human plasma, the content of Copper Tripeptide-1(GHK-Cu) was 200 μ g / ml at the age of 20. By the age of 60, the level dropped to 80 μ g / ml. Copper Tripeptide-1(GHK-Cu) can promote the activation of wound recovery, the attraction of immune cells, anti-oxidation and anti-inflammatory effects, stimulate the synthesis of collagen and glycosaminoglycan in the pores and skin fibroblasts, and promote the commercialization of blood vessels. GHK is a safe and widely studied compound, which plays an active and health promoting role in many tissues and systems. For decades, it has been widely used in human anti-aging and cosmetics, without any side effects, and can easily be added to cream, liposomes, foam or subcutaneous injection.