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Antioxidants

L-Glutathione Reduced

L-Glutathione Reduced is a tripeptide composed of glutamic acid, cysteine and glycine. It is a small peptide containing sulfhydryl group. L-Glutathione Reduced plays two important roles: integrated detoxification and anti-oxidation.
Product parameters
Product Name: Glutathione
Other Names: L-Glutathione Reduced; GSH; Reduced Glutathione
CAS No.: 70-18-8
Molecular Weight: 307.32
Molecular Formula: C10H17N3O6S
Purity/ Assay: 98.0-101.0%
Application: Cosmetics, Food and Pharma
Packing Size: 1kg
  • COA of L-Glutathione Reduced-Shanghai CosromaDownload
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Description
L-Glutathione Reduced is a tripeptide composed of glutamic acid, cysteine and glycine. It is a small peptide containing sulfhydryl group. L-Glutathione Reduced plays two important roles: integrated detoxification and anti-oxidation.
 
Integrated detoxification
The sulfhydryl group on the cysteine in the structure is its active group (so L-Glutathione Reduced is often abbreviated as G-SH), which is easy to be complexed with heavy metal salts such as iodoacetic acid, mustard gas (a kind of toxic gas), lead, mercury, arsenic, etc., and has an integrated detoxification effect. L-Glutathione Reduced (especially L-Glutathione Reduced in hepatocytes) can be combined with some drugs (such as paracetamol), toxins (such as free radicals, heavy metals) and participate in biotransformation, so as to transform harmful poisons into harmless substances and excrete them out of the body.
 
Anti-oxidation.
The other main physiological function of L-Glutathione Reduced is as an important antioxidant in the body. It can clear away the free radicals in the body, clean and purify the environmental pollution in the body, so as to improve the physical and mental health of people.Because Reduced L-Glutathione Reduced itself is easy to be oxidized by some substances, it can protect the sulfhydryl group in many protein and enzyme molecules from being oxidized by harmful substances such as free radicals, so that protein and enzyme molecules can play their physiological functions.There are a lot of L-Glutathione Reduced in human red blood cells, which is of great significance to protect the sulfhydryl group of protein on the membrane of red blood cells from reduction and hemolysis, and to protect hemoglobin from oxidation by hy-drogen peroxide, free radicals and so on, so that it can continuously and normally transmit oxygen.Under the action of oxidants such as hy-drogen peroxide, part of hemoglobin in red blood cells is oxidized from divalent iron to trivalent iron, which changes hemoglobin into methemoglobin, thus losing the ability of carrying oxygen.Reduced L-Glutathione Reduced can not only directly combine with oxidants such as hy-drogen peroxide to produce water and oxidized L-Glutathione Reduced, but also reduce methemoglobin to hemoglobin.

In addition, vitamin C is an important antioxidant in the body.Since vitamin C can be hy-drogenated or dehy-drogenated reversibly, it plays an important role in many redox reactions in vivo.For example, the active group of many enzymes is sulfhydryl (- SH), vitamin C can maintain the activity of enzymes while - SH is in the reducing state; vitamin C can transform oxidized L-Glutathione Reduced into Reduced L-Glutathione Reduced (GSH), reducing hy-drogen peroxide (H2O2) produced by metabolism of the body; vitamin C can also protect vitamin A, e and some B vitamins from oxidation.Therefore, when L-Glutathione Reduced is used together with vitamin C, its efficacy can be improved.

At present, L-Glutathione Reduced has been widely used in clinic. In addition to using its sulfhydryl group to chelate heavy metals, fluorides, mustard gas and other toxins, it is also used in hepatitis, hemolytic diseases, keratitis, cataracts and retinal diseases as auxiliary treatment drugs.L-Glutathione Reduced is used to treat and prevent the following diseases:
1, detoxification: L-Glutathione Reduced has detoxification effect on acrylonitrile, fluoride, mustard gas, carbon monoxide, heavy metals, organic solvents, arsenic agents (such as traditional Chinese medicine, such as pyrrolidine, realgar), lead, mercury, sulfur, phosphorus poisoning, etc.
2, radiation disease and radiation protection: it is used for radiation therapy, radiation medicine or leukopenia caused by the use of tumor medicine and inflammation of bone marrow tissue caused by radiation. L-Glutathione Reduced can improve its symptoms, and has the effects of anti radiation and sunlight. At the same time, L-Glutathione Reduced can also be used to treat scleroderma, dermatomyositis, lupus erythematosus and other diseases caused by radiotherapy. For those who may be exposed to ionizing radiation, L-Glutathione Reduced can also be injected as a preventive measure.
3, protect the liver: L-Glutathione Reduced can inhibit the formation of fatty liver and improve the symptoms of toxic hepatitis and infectious hepatitis.
4, anti allergy: L-Glutathione Reduced can correct the imbalance of acetylcholine and cholinesterase, so as to eliminate the allergic symptoms caused by this imbalance.L-Glutathione Reduced can be used in the treatment of lupus erythematosus, scleroderma, dermatomyositis, arthritis and other autoimmune diseases.
5, improve the course and symptoms of some diseases: L-Glutathione Reduced can improve the symptoms of leukopenia, anoxia, nausea and vomiting, pruritus and other symptoms caused by liver diseases.At the same time, L-Glutathione Reduced can improve diabetic complications, such as retinal diseases, peripheral nerve diseases, etc.
6, beauty care and skin care: L-Glutathione Reduced is not only commonly used in clinical treatment, but also can be used as drug cosmetics.Because L-Glutathione Reduced can chelate free radicals, heavy metals and other internal and external toxins in the body, prevent skin pigmentation, prevent the formation of new melanin and reduce its oxidation, so L-Glutathione Reduced has a good effect of skin care, beauty and rejuvenation whether it is used internally or externally.
7, increase vision and eye diseases: L-Glutathione Reduced can promote the metabolism of eye tissue, inhibit the instability of crystal protein sulfhydryl group, so L-Glutathione Reduced can be used for keratitis, corneal trauma, etc., and prevent the development of cataract and retinal diseases.For this kind of disease, we should start to take these antioxidants frequently before entering the old age, or inject L-Glutathione Reduced frequently, which can play a preventive role.At the same time, it also has a good effect of increasing vision.
8, anti-aging effect: when the body is aging, the production of various free radicals in the body increases. As human waste, free radicals are one of the important endotoxins in the body.Because L-Glutathione Reduced can remove free radicals, heavy metals and other toxins, L-Glutathione Reduced is suitable for anti-aging and has a good effect.

Because the chemical nature of L-Glutathione Reduced is small molecule peptide, it is easy to be absorbed by the skin through the cell membrane for external use. It is very effective as a cosmetic external use, and its skin care effect is excellent.At the same time, L-Glutathione Reduced, as a small molecular peptide, can be absorbed by oral administration without digestion, so oral administration of L-Glutathione Reduced is effective.Therefore, in the use of L-Glutathione Reduced for anti-aging and beauty skin care, both internal and external use of its efficacy is outstanding.
 
In addition, L-Glutathione Reduced can play an unexpected role in food.
1. L-Glutathione Reduced can play a reducing role when added to the flour products. L-Glutathione Reduced not only shortens the time of making bread to one-half or one-third of the original time, greatly improves the working conditions, but also plays the role of strengthening food nutrition and other functions.
2. Adding L-Glutathione Reduced to yoghurt and infant food is equivalent to vitamin C, which can play a stabilizing role.
3. Mixing L-Glutathione Reduced into fish cake can prevent the color from deepening.
4. Adding L-Glutathione Reduced to meat products, cheese and other foods has the effect of strengthening flavor.